Biology

Gene to Protein

Lesson Plan

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State Standards:


Essential Questions:

Lesson Questions:

Introduction:

The biological world is a diverse place. Every organism is different. DNA is the source of these differences. However, proteins are the raw material for the diversity of life.

Lesson Experiences:

You are going to discover the process of protein synthesis (the making of proteins) and how proteins are important for organisms. Protein synthesis is commonly referred to as transcription and translation. Each part is essential for the production of proteins. For your investigation you will use a NOVA Science Now video, use a gene transcription and translation interactive website, and create a model and digital animation to understand how protein synthesis works. Your final product will be an iMovie animation of protein synthesis created and narrated by your group and you.

  1. First you will be assigned to a group of three and a computer station.

  2. Once in your group. Watch the following movie.
    Nova Science NOW DNA movie still

    Answer the three questions below:
    • What does the monk represent? What do the chefs represent?
    • What role did the petunia play in the discovery of RNAi?
    • How does RNAi work?
    • Why did cells evolve this mechanism?

  3. Now you will take the knowledge from the video and apply it to an interactive protein synthesis game. Go to DNA Transcription simulator U. of Utah thumbnail
    Work through the steps on the website. Write out the DNA sequence that you see on the first screen. Then make sure to write down all of the steps you take in your science journal. You will need this for the next part of the activity.

  4. Now, it is your turn to make an animation of transcription and translation. Your job is to model transcription and translation on the lab tables. The lab tables will act as your picture frame/story board. You will need to describe the process of protein synthesis using drawings, objects, construction paper, modeling clay, etc to demonstrate the steps. It is up to you what you use to represent the steps. You must use biology vocabulary in your animation.
    1. For example, maybe your group will decide that the nucleus is important for protein synthesis. You might want to draw and label the nucleus with colored chalk. Or maybe you want to use construction paper to make a big pink nucleus.
      You may be as creative as you want with the narration (school appropriate of course) and the pieces involved in the process.

  5. At each step (whenever you move or change something) you should take a picture with the digital camera. When you finish you should have a bunch of photos.
  6. At each step (whenever you move or change something) you should take a picture with the digital camera. When you finish you should have a bunch of photos.
  7. Use these photos to create an iMovie. Refer to if you do not know how to make an iMovie.How to make an iMovie Slideshow - About.com thumbnail
  8. Be ready to show your iMovie to the class.

Conclusion:

After completing this lesson you should be able to explain the phrase “gene to protein”. Make sure you can discuss the answer to this question. If you would like to go further with your understanding of protein synthesis, go to
How does a firefly make light? interactive movie thumbnail
.

Assessments:

Rubric

You will be able to....

Exemplary
4

Proficient
3

Partially Proficient
2

Incomplete
1

Weighting

Content

Creativity and original content enhance the purpose of the iMovie in an innovative way. Accurate information and clearly described concepts are presented. Vocabulary enhances content.

Accurate information is provided very clearly to the audience.

Vocabulary is appropriate.

Some information is accurate or long- winded—loses focus.

Vocabulary is adequate.

Information is inaccurate or difficult to follow.

Vocabulary is inappropriate for the audience.

___

Delivery

Well rehearsed, smooth delivery in a conversational style. Highly effective enunciation and presenter’s speech is clear and intelligible.

Rehearsed, smooth delivery. Enunciation, expression, and pacing are effective throughout the iMovie

Appears unrehearsed with uneven delivery. Enunciation, expression, and pacing are sometimes distracting during the iMovie.

Delivery is hesitant, and choppy and sounds like the presenter is not prepared. Enunciation of spoken word is distant and muddled and not clear. Expression and pacing are distracting throughout the iMovie.

___

Technical Production

No background noise or distractions.
Transitions are smooth and spaced without noise or dead space.

Volume of voice, music, and effects enhance the presentation.

Minimal background noise or distractions.
Transitions are smooth with minimal amount of noise or dead space.

Volume is acceptable.

Some background noise or distractions.
Transitions are uneven—noise or dead space evident.

Volume is occasionally inconsistent.

Noisy background noise or distractions.
Transitions are abrupt and background noise needs to be filtered.

Volume changes are highly distracting.

___

Group/Partner
Work

Members contribute equally to the finished product and share equal time speaking.

Members came close to contributing equally to the finished product and sharing time speaking.

Members who did not participate will not receive the same grade as participating member.

Members who did not participate will not receive the same grade as participating member.

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Resources:

Image Credit: Myoglobin protein - wikepedia